Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
Call emergency services for severe trouble breathing, chest pain, fainting, sudden one-sided weakness, difficulty speaking, a seizure, confusion, uncontrolled bleeding, or signs of a serious allergic reaction such as swelling of the face or throat.
These symptoms can have many causes and require immediate evaluation.
Contact the treating clinician promptly for new or clearly worsening symptoms, a possible medication reaction, signs of infection, or a flare that is not responding to the agreed management plan.
Fever or infection symptoms deserve particular attention when taking medicines that suppress the immune system.
Seek urgent medical assessment for symptoms such as a new painful swollen leg, sudden vision change, significant weakness, blood in the urine, persistent vomiting, or rapidly worsening shortness of breath.
Routine follow-up may include reviewing symptoms, examining affected organs, checking laboratory results, monitoring medicine safety, and updating vaccinations and preventive care.
Keep a current list of medicines and supplements, including nonprescription products.
A brief record of symptoms, possible triggers, and effects on daily activities can help during appointments.
Every sign above is quoted from the sofidex article on Autoimmune diseases. If you are not sure, err upward — it is always reasonable to be checked.