Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
Emergency symptoms are different from routine follow-up concerns.
Seek immediate care for trouble breathing, severe or persistent chest pain, confusion, seizures, fainting, severe dehydration, or a rapidly worsening illness.
Tell emergency clinicians about the autoinflammatory condition and all current medicines, but do not assume that a new fever is caused by the condition.
Contact your usual clinical team promptly if attacks become more frequent, symptoms change from their usual pattern, treatment stops working, or medication side effects develop.
Fever, cough, painful urination, unusual weakness, or other possible infection symptoms should be reported promptly when taking medicine that suppresses immune activity.
Routine follow-up is important even when symptoms are controlled.
The schedule depends on the condition and treatment.
Visits may review flare frequency, daily functioning, medication use, side effects, growth in children, and any new organ symptoms.
The article also says
Monitoring may include blood counts, liver and kidney tests, inflammatory markers, and urine testing for protein.
People receiving immune-modifying medicines may need infection screening and medication-specific monitoring.
Hearing, eye, joint, or neurologic assessments may be appropriate for certain diseases.
Every sign above is quoted from the sofidex article on Autoinflammatory diseases. If you are not sure, err upward — it is always reasonable to be checked.