Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Seek emergency help for:
Trouble breathing, noisy breathing or blue-grey lips
Sudden inability to swallow liquids or saliva
Severe weakness, confusion, fainting or difficulty waking
Signs of a serious spreading infection, such as fever with rapid deterioration
Bleeding that does not stop with gentle, appropriate pressure
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Arrange prompt medical advice for a new or changing wound, worsening pain, difficulty eating, poor weight gain, constipation that is not settling, eye pain or reduced movement.
Increasing redness, warmth, swelling, pus, bad odour or fever may indicate infection.
A wound that becomes raised, unusually hard, repeatedly bleeds, grows quickly or does not heal in its usual way needs urgent assessment.
This is particularly important for people with recessive dystrophic EB because of the risk of squamous cell carcinoma.
3
Does any of this apply?
Book an appointment
Routine blistering without these warning signs is usually managed through the established wound-care plan and specialist follow-up.
Every sign above is quoted from the sofidex article on Epidermolysis bullosa. If you are not sure, err upward — it is always reasonable to be checked.