Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Call emergency services for:
Sudden shortness of breath, chest pain, or coughing up blood
One-sided leg swelling or pain with breathing symptoms
Severe breathing difficulty caused by swelling
Collapse, confusion, or inability to wake normally
These symptoms can suggest a blood clot, severe infection, or a major disturbance in fluid balance.
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Seek urgent same-day medical advice for:
Fever or signs of infection while taking immune-suppressing medicine
A major decrease in urine output
Rapidly worsening swelling
Vomiting or diarrhoea that makes it difficult to keep fluids down
New redness, warmth, or pain in a swollen area
Symptoms of very high or very low blood pressure, such as fainting or a severe headache
3
Does any of this apply?
Book an appointment
Arrange a routine medical review if you develop new puffiness, ankle swelling, persistent foamy urine, or unexplained weight gain.
If you already have minimal change disease, report a return of protein in your urine or swelling according to your follow-up plan.
Every sign above is quoted from the sofidex article on Minimal change disease. If you are not sure, err upward — it is always reasonable to be checked.