sofidexFor patientsAre you a clinician? Clinical site

Warning-sign checks

Multiple endocrine deficiency syndrome: when to get help

Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.

  1. 1

    Is any of this happening now?

    Call 911

    Call emergency services for symptoms that may indicate adrenal crisis, DKA, or severe low calcium.

    These include:

    • Fainting, confusion, extreme weakness, or severe dizziness
    • Repeated vomiting or inability to keep steroid medicine down
    • Severe abdominal pain with known or possible adrenal insufficiency
    • Deep or rapid breathing, vomiting, marked drowsiness, or fruity-smelling breath
    • A seizure, severe muscle spasms, or difficulty breathing

    If you have an adrenal emergency plan, follow it while emergency help is being arranged.

    Do not delay emergency care to wait for symptoms to improve.

    Other emergency signs, for anyone
    • Someone who is struggling to breathe, gasping, choking, or cannot get words out
    • Someone who has chest pain, tightness or pressure lasting more than a few minutes
    • Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
    • Someone who is unconscious, or cannot be woken
    • Someone who is bleeding heavily and it will not stop with firm pressure
    • Someone who has had a seizure that will not stop, or does not wake up afterwards
    • Someone who has lips or skin that look pale, blue, grey or blotchy
    • Someone who you believe has taken an overdose or swallowed something poisonous
  2. 2

    Is any of this happening?

    Be seen today

    Seek prompt medical advice for new excessive thirst and urination, unexplained weight loss, frequent low-glucose episodes, increasing dizziness, persistent vomiting, or tingling and muscle cramps.

  3. 3

    Does any of this apply?

    Book an appointment

    Routine follow-up is appropriate for gradual symptoms such as increasing tiredness, cold sensitivity, constipation, menstrual changes, hair loss, recurring thrush, or changes in skin colour.

    Arrange an earlier review if these symptoms are persistent or worsening.

Every sign above is quoted from the sofidex article on Multiple endocrine deficiency syndrome. If you are not sure, err upward — it is always reasonable to be checked.