Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
These changes usually need assessment, but they are not automatically an emergency.
Get emergency help for:
Severe difficulty breathing, chest pain, fainting, or blue-grey lips
Sudden facial drooping, arm weakness, speech trouble, or confusion
Heavy bleeding that does not stop
Vomiting blood or passing black, tar-like stools
Sudden severe abdominal pain, especially under the left ribs
A painful swollen leg with sudden breathlessness
These symptoms can have causes other than myelofibrosis, but they need immediate assessment.
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Contact your haematology team promptly if you develop a clear increase in tiredness, abdominal swelling, night sweats, weight loss, bruising, bleeding, or infections.
Seek urgent medical advice for a fever or signs of infection, particularly if you have been told that your white-cell count is low or you are taking treatment that affects immunity.
Follow any specific fever plan given by your treatment centre.
Every sign above is quoted from the sofidex article on Myelofibrosis. If you are not sure, err upward — it is always reasonable to be checked.