Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
Call emergency services for heavy bleeding that will not stop, trouble breathing, fainting, confusion, chest pain, or signs of a severe allergic reaction such as swelling of the tongue or throat.
Seek urgent advice for bleeding that continues despite following the pressure and bleeding-control instructions provided by your facility.
The article also says
Contact your healthcare team during normal service hours if soreness, blockage, or discharge is not improving as expected.
Also call if you develop increasing redness, swelling, worsening pain, pus-like drainage, or a fever.
Every sign above is quoted from the sofidex article on Nasal mucosal biopsy. If you are not sure, err upward — it is always reasonable to be checked.