Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
Call emergency services for severe breathlessness, chest pain, fainting, a seizure, or marked confusion.
Ask for prompt medical advice if you have vomiting, diarrhoea, fever, or poor fluid intake and are unsure how to manage diabetes or kidney-related medicines.
Seek urgent assessment for a sudden reduction in urine, rapidly increasing swelling, repeated vomiting, or a sudden unexplained change in glucose levels.
These symptoms can occur with serious fluid, heart, electrolyte, or glucose problems and should not wait for a routine appointment.
Arrange routine follow-up if you notice persistent foamy urine, new mild ankle swelling, increasing tiredness, or blood pressure readings repeatedly above your agreed range.
Also seek advice if treatment side effects are making it difficult to take your medicines.
Every sign above is quoted from the sofidex article on Nephropathy diabetic. If you are not sure, err upward — it is always reasonable to be checked.