Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Call emergency services for:
Severe or sudden breathlessness
Chest pain that is new, severe, or persistent
Fainting, especially during activity
A sustained rapid or very slow heartbeat with weakness or dizziness
Sudden facial drooping, arm weakness, speech difficulty, or other stroke signs
These symptoms can have several causes.
Emergency assessment is needed rather than waiting for a routine amyloidosis appointment.
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Seek a prompt appointment for new or worsening numbness, weakness, balance problems, diarrhoea, constipation, weight loss, ankle swelling, reduced exercise tolerance, or dizziness when standing.
Contact your care team promptly if symptoms are progressing between planned visits or treatment side effects are interfering with eating, walking, sleep, or daily activities.
3
Does any of this apply?
Book an appointment
Arrange routine medical follow-up if you have a known `TTR` variant, even if you feel well.
Every sign above is quoted from the sofidex article on Prealbumin tyr-77 amyloidosis. If you are not sure, err upward — it is always reasonable to be checked.