Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Go to emergency care if you have:
Severe or rapidly worsening flank pain with fever
An inability to urinate or a sudden major reduction in urine
Heavy bleeding, large blood clots, or difficulty passing urine
Confusion, fainting, marked weakness, or difficulty breathing
Persistent vomiting that prevents you from keeping fluids down
These signs may indicate blocked urine flow, a serious infection, heavy bleeding, or acute loss of kidney function.
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Arrange prompt medical assessment if you notice blood in your urine, even if it is painless or happens only once.
Also seek advice for persistent flank pain, repeated urinary infections, painful urination, or possible tissue in the urine.
These symptoms do not prove papillary necrosis, but they need an explanation.
Seek urgent same-day care for fever or chills with flank pain, particularly if you have diabetes, a sickle cell condition, reduced immunity, or known urinary blockage.
3
Does any of this apply?
Book an appointment
And for anyone, someone who:
is having side effects from a medicine, or is struggling to take it as prescribed
Every sign above is quoted from the sofidex article on Renal papillary necrosis. If you are not sure, err upward — it is always reasonable to be checked.